TTC healthFertilityLife

A new study has revealed women who have a BRCA1 gene mutation have less eggs than those who don’t. The results of the study, published within the Journal of Clinical Oncology, mean affected women may have a reduced window of opportunity to have children. Here, we’ll look at what this latest research means, and how it impacts fertility preservation.

Understanding the latest study

The study included a total of 824 women who had undergone BRCA testing. It was revealed that 246 of the women tested positive for either the BRCA1 or BRCA2 mutation. The other 578 tested negative.

The majority of the women were diagnosed with breast cancer. It was discovered that those who did have a BRCA mutation had a 2.04 ng/mL (14.6pmol/l) anti-Müllerian hormone level. Those who didn’t have the mutation had a hormone level of 3.36 ng/mL (24pmol/L).

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